Fig. 2.

Effects of Keguan-1 on the histological changes in LPS-induced ALI mice. Representative images of mice lung tissue stained using HE after 24 h of LPS administration. (A) Control; (B) LPS; (C) LPS + 1.25 g/kg Keguan-1; (D) LPS + 2.5 g/kg Keguan-1; (E) LPS + 5.0 g/kg Keguan-1; (F) LPS + 2.5 mg/kg DXM. (G) Lung injury scores of mice in each group. The upper panel is low magnification (scale bar = 100 μm) of the images, the areas inside the boxes are shown in the lower panel at high magnification (scale bar = 50 μm). The data are presented as the mean ± SEM. ^##P < 0.01 vs. control; ^∗P < 0.05 and ^∗∗P < 0.01 vs. LPS group.