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. 2021 Nov 9;12(23):2321–2322. doi: 10.18632/oncotarget.27474

Figure 5. Glutathione (GSH) metabolism analysis after treatment with paclitaxel in uterine serous carcinoma cells.

Figure 5

(A) Each cell line was treated with 15 nM paclitaxel or control vehicle for 24 h. Blue bars represent USPC-1 cells (control), red bars represent USPC-1 cells treated with paclitaxel, green bars represent PTX-1 cells (control) and yellow bars represent PTX-1 cells treated with paclitaxel. Values in the graphs represent the means ± SD of three independent experiments. (B) Concentrations of cysteine, GSH, GSSG and total glutathione in USC cells after treatment with paclitaxel. GSH/GSSG (glutathione redox ratio) = [GSH]/[GSSG]. Total glutathione = [GSH] + 2 × [GSSG], * P < 0.05. N.D.: not detected.