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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Cell Immunol. 2021 May 21;366:104383. doi: 10.1016/j.cellimm.2021.104383

Figure 1. GPs loaded with myelin autoantigens induce clinical EAE disease comparable to CFA-induced EAE.

Figure 1.

EAE was induced by s.c. injection of myelin autoantigens either packaged into GPs or emulsified in CFA. Mice were scored daily for clinical EAE. Shown are the clinical disease scores for (A) C57BL/6 active disease with 200 μg MOG35–55 administered once for CFA and twice for GP and (B) SJL active disease with 100 μg PLP139–151 administered once for CFA and twice for GP. Data shown are EAE disease score ± SD of one experiment representative of two independent C57BL/6 experiments and three independent SJL experiments (n=10–15 per group, unpaired t-test performed for each day).