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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Cell Immunol. 2021 May 21;366:104383. doi: 10.1016/j.cellimm.2021.104383

Figure 4. Antigen-specific Th1 and Th17 immune responses are comparable in mice immunized with CFA and GP adjuvants.

Figure 4.

Immunization of myelin autoantigens with either CFA or GP adjuvants elicited similar antigen-specific IFN-γ and IL-17 responses on day 24 post immunization as measured by spleen ELISPOT for both (A and C) C57BL/6 immunized with MOG35–55 or (B and D) SJL mice immunized with PLP139–151. Experiments shown are two representative studies of four independent C57BL/6 experiments and one representative of three independent SJL experiments with similar results, n=3–5 mice per group for each experiment analyzed by unpaired t-test.