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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Prog Retin Eye Res. 2020 Sep 18;82:100903. doi: 10.1016/j.preteyeres.2020.100903

Figure 5. Effect of FN and Col IV antisense oligos on integrin α5 and α3 expression in RRECs.

Figure 5.

Representative western blot image demonstrates that expression levels of (A) FN and α5 integrin, as well as those of (B) Coll IV and α3 integrin, are increased in cells grown in HG medium compared to that of cells grown in normal medium. Bar graphs representing cumulative data indicate that reducing (C) FN and (E) Col IV overexpression using antisense oligos decrease (D) α5 and (F) α3 integrin levels, respectively. Data is presented as mean ± standard deviation; *p<0.05. **p<0.01. N: normal media; HG: high glucose media; As-FN: HG media + antisense Col IV oligos; As-Col: HG media + antisense Col IV oligos; HG+Ran: HG medium + random oligos.