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. 2021 Nov 15;21:371. doi: 10.1186/s12890-021-01745-7

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Effects of MgIG on body weight and pulmonary function in COPD rats. A Changes of body weight of the rats during 30-day COPD model construction. B Changes of body weight of the rats in different groups during treatment. C Comparison of FEV0.3 of rats in different groups after treatment for pulmonary function evaluation. D Comparison of FVC of rats in different groups after treatment for pulmonary function evaluation. E, Comparison of FEV0.3/FVC of rats in different groups after treatment for pulmonary function evaluation. All data were presented as mean ± standard deviation (n = 10 in each group). Statistical significance of differences were determined by one-way ANOVA. ***P < 0.001 and **P < 0.01 compared to CON group. ^###P < 0.001, ^##P < 0.01 and ^#P < 0.05 compared to MDL group. Abbreviations: FEV0.3, forced expiratory volume in 0.3 s; FEV0.3/FVC, forced expiratory volume in 0.3 seconds/forced vital capacity; FVC, forced vital capacity