Table 2.

Discovery cohort: means of CD8+ T-cell densities according to their spatial distribution and immune phenotype within the discovery cohort (A) and the corresponding p values using the Holm–Šídák method for multiple comparisons (B).

A
Mean CD8+ T cells/μm2	Immune phenotypes
	Desert (n = 34)	Excluded (n = 62)	Inflamed (n = 18)
Tumor compartments
iCD8+	0.00002	0.0002	0.0006
sCD8+	0.0002	0.002	0.005
imCD8+	0.0006	0.002	0.003

B
p values	Immune phenotypes
	Desert vs. excluded	Desert vs. inflamed	Excluded vs. inflamed
Tumor compartments
iCD8+	ns	<0.05	ns
sCD8+	<0.0001	<0.0001	<0.01
imCD8+	<0.0001	<0.0001	ns

Invasive margin (im) CD8+ for desert n = 24, excluded n = 54, and inflamed n = 13.