Table 3.
Postoperative quality of life among patients with indeterminate thyroid nodules and suspicious molecular test results based on final surgical pathology
| ThyPro-39 QOL scale | Baselinea [n = 36] | Benign surgical pathology [n = 23] | Malignant surgical pathology [n = 12] |
|---|---|---|---|
| Goiter | |||
| Mean ± SD | 21.4 ± 23.9 | 8.3 ± 9.7* | 12.5 ± 12.3 |
| Anxiety | |||
| Mean ± SD | 35.2 ± 28.0 | 26.5 ± 24.9 | 19.5 ± 22.4 |
| Depression | |||
| Mean ± SD | 38.1 ± 23.5 | 30.3 ± 21.0 | 20.4 ± 13.0* |
| Emotional susceptibility | |||
| Mean ± SD | 33.3 ± 22.2 | 29.9 ± 23.7 | 24.0 ± 20.6 |
| Impaired social life | |||
| Mean ± SD | 20.4 ± 24.4 | 13.9 ± 20.7 | 5.9 ± 11.3 |
| Impaired daily life | |||
| Mean ± SD | 17.6 ± 22.5 | 10.9 ± 16.6 | 6.8 ± 12.2 |
| Appearance | |||
| Mean ± SD | 19.3 ± 21.8 | 27.6 ± 26.6 | 13.1 ± 20.6 |
Higher score corresponds to worse QOL. Postoperative surveys were completed at a median (interquartile range) of 8 months (5–12) after thyroidectomy
aBaseline = 0–4 months after FNA and prior to thyroidectomy
bp < 0.05 compared with baseline QOL
ThyPro-39 Thyroid-Related Patient-Reported Outcome, 39-item version, QOL quality of life, SD standard deviation, FNA fine needle aspiration