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. 2021 Nov 1;11:748061. doi: 10.3389/fonc.2021.748061

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Copyright © 2021 Lin, Wang, Chen, Gong, Chen, Shi, Lan, Chen, Xiong, Sun and Wan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Trends in Annual Glioma Mortality Rates. (A) represents glioma mortality (1995-2018), overall and by histologic type based on cases diagnosed during 1975-2018. (B) represents glioblastoma mortality (1995-2018) by age group based on cases diagnosed during 1975-2018. (C) represents glioblastoma incidence by tumor extension (1995-2015) and size (1995-2018) based on cases diagnosed during 1983-2015 and 1983-2018, respectively. Each point represents the observed incidence-based mortality rates (100,000 person-years). The slope of the lines represents the annual percent change (APC). All rates are age-adjusted to the 2000 US standard population.