Table 2.
Univariate analyses of risk factors associated with overall survival.
| Variables | LSCC | RSCC | ||||
|---|---|---|---|---|---|---|
| OS% | 95% CI | P value | OS% | 95% CI | P value | |
| Age | 0.008 | 0 | ||||
| ≤67 | 96.10 | 92.35–100 | 87.93 | 81.77–94.56 | ||
| >67 | 85.33 | 78.26–93.05 | 73.5 | 66.16–81.65 | ||
| Grade | 0.309 | 0.098 | ||||
| I | 100 | 100–100 | 82.6 | 68.22–100 | ||
| II | 90.74 | 86.23–95.49 | 83.35 | 77.75–89.35 | ||
| III | 89.23 | 78.13–100 | 67.79 | 55.48–82.84 | ||
| pTNM | 0 | 0.002 | ||||
| I | 92.43 | 82.47–100 | 100 | 100–100 | ||
| II | 99.17 | 97.57–100 | 84.72 | 78.48–91.44 | ||
| III | 80.98() | 72.44–90.53 | 70.71 | 61.82–80.88 | ||
| IV | / | / | / | |||
| Positive lymph node | 0 | 0 | ||||
| 0 | 97.61 | 94.87–100 | 88 | 82.7–93.64 | ||
| >0 | 81.45 | 73.07–90.79 | 68.05 | 59.04–78.43 | ||
| LODDS | 0 | 0 | ||||
| ≤−0.9138 | 96.84 | 93.71–100 | 88.85 | 84.29–93.65 | ||
| ≤−0.2373 | 87.3 | 77.96–97.75 | 64.62 | 49.52–84.33 | ||
| >−0.2373 | 57.93 | 38.98–86.1 | 30.13 | 15.15–59.93 | ||
| Tumor size | 0.422 | 0.738 | ||||
| <5 cm | 93.63 | 89.54–97–91 | 79.92 | 73.2–87.26 | ||
| ≥5 cm | 86.79 | 78.86–95.51 | 80.47 | 73.09–88.59 | ||
| Ki-67 | 0.896 | 0.603 | ||||
| (+, ≤25) | 100 | 100–100 | 75 | 49.61–100 | ||
| (++, ≤50) | 86.4 | 76.52–97.54 | 73.35 | 62.32–86.35 | ||
| (+++, ≤75) | 94.17 | 89.31–99.3 | 79.76 | 70.7–89.98 | ||
| (++++, ≤100) | 89.85 | 82.08–98.36 | 81.86 | 73.17–91.59 | ||
| NA | ||||||
| CA724 | 0.386 | 0.039 | ||||
| Negative | 94.69 | 90.82–98.73 | 83.44 | 77.23–90.14 | ||
| Positive | 85.58 | 73.39–99.79 | 83.35 | 72.45–95.89 | ||
| CEA | 0.48 | 0 | ||||
| Negative | 94.66 | 90.13–99.43 | 89.77 | 84.1–95.81 | ||
| Positive | 88.43 | 80.82–96.75 | 68.44 | 57.98–80.8 | ||
| CA199 | 0.357 | 0.001 | ||||
| Negative | 93.75 | 89.99–97.67 | 85.43 | 79.67–91.6 | ||
| Positive | 74.87 | 53.13–100 | 62.79 | 47.74–82.57 | ||
| CA50 | 0.759 | 0.275 | ||||
| Negative | 93.47 | 88.10–99.17 | 83.61 | 74.91–93.31 | ||
| Positive | 84 | 65.62–100 | 77.89 | 63.5–95.54 | ||
| CA125 | 0.002 | 0.164 | ||||
| Negative | 93.91 | 88.72–99.41 | 84.63 | 76.73–93.34 | ||
| Positive | 58.33 | 30–100 | 75.1 | 57.63–97.86 | ||
| TSP | 0.508 | 0.004 | ||||
| ≤50% | 92.11 | 87.72–96.71 | 84.33 | 78.69–90.38 | ||
| >50% | 90.05 | 82.71–98.03 | 70.56 | 60.85–81.83 | ||
| CDX2 | 0.109 | 0.585 | ||||
| Negative | 85.71 | 63.34–100 | 79.06 | 62.7–99.69 | ||
| Positive | 93.41 | 89.72–97.25 | 79.57 | 73.9–85.68 | ||
| MLH1 | 0.98 | 0.678 | ||||
| Negative | 86.88 | 71.35–100 | 85.26 | 74.99–96.92 | ||
| Positive | 92.03 | 87.94–96.31 | 79.51 | 73.44–86.08 | ||
| MSH2 | 0.744 | 0.998 | ||||
| Negative | 100 | 100–100 | 89.64 | 76.95–100 | ||
| Positive | 89.96 | 85.31–94.85 | 79.23 | 73.45–85.46 | ||
| ERCC1 | 0.502 | 0.7 | ||||
| Negative | 90 | 77.77–100 | 77.59 | 63.15–95.31 | ||
| Positive | 90.24 | 85.32–95.44 | 82.24 | 76.66–88.24 | ||
| NM23 | 0.91 | 0.068 | ||||
| Negative | 83.33 | 64.7–100 | 71.79 | 51.77–99.57 | ||
| Positive | 91.84 | 87.15–96.8 | 80.43 | 74.51–86.83 | ||
| COX2 | 0.408 | 0.613 | ||||
| Negative | 96 | 88.62–100 | 78.75 | 62.2–99.7 | ||
| Positive | 90.4 | 84.25–97 | 83.53 | 77.47–90.06 | ||
| c-MET | 0.78 | 0.694 | ||||
| Negative | 91.85 | 85.26–98.96 | 82.58 | 74.69–91.31 | ||
| Positive | 88.74 | 81.28–96.88 | 76.32 | 67.55–86.22 | ||