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. 2021 Nov 1;12:721949. doi: 10.3389/fgene.2021.721949

TABLE 3.

Univariate and multivariate analysis associated with overall survival.

Variables	Univariate analysis		Multivariate analysis
Variables	p value	HR (95% CI)	p value	HR (95% CI)
Age (years)	0.80	0.86 (0.26–2.80)	0.86	1.12 (0.33–3.79)
≥50 vs < 50	0.80	0.86 (0.26–2.80)	0.86	1.12 (0.33–3.79)
Gender	0.26	1.43 (0.76–2.66)	0.93	1.03 (0.53–2.01)
Female vs Male	0.26	1.43 (0.76–2.66)	0.93	1.03 (0.53–2.01)
Pathologic Stage	0.0003	3.45 (1.78–6.70)	0.01	2.63 (1.22–5.66)
III-IV vs I-II	0.0003	3.45 (1.78–6.70)	0.01	2.63 (1.22–5.66)
Lymphatic Invasion	0.004	2.81 (1.39–5.68)	0.17	1.75 (0.78–3.90)
Yes vs No	0.004	2.81 (1.39–5.68)	0.17	1.75 (0.78–3.90)
Risk score	0.007	2.53 (1.29–4.99)	0.005	2.67 (1.35–5.30)
High vs Low	0.007	2.53 (1.29–4.99)	0.005	2.67 (1.35–5.30)

Bold indicates significance. Abbreviations: CI, confidence interval; HR, hazard ratio.