Table 3.
Description | Gene Markers | Cor | P |
---|---|---|---|
CD8+ T cell | CD8A | 0.021 | 0.839 |
CD8B | −0.075 | 0.463 | |
T cell (general) | CD3E | −0.023 | 0.822 |
CD2 | 0.027 | 0.792 | |
CD3D | −0.014 | 0.889 | |
B cell | CD19 | −0.086 | 0.403 |
CD79A | −0.110 | 0.283 | |
Monocyte | CD86 | 0.170 | 0.097 |
CD115(CSF1R) | 0.132 | 0.197 | |
CCL2 | 0.036 | 0.730 | |
CD68 | 0.004 | 0.973 | |
IL10 | 0.023 | 0.825 | |
M1 Macrophage | INOS(NOS2) | −0.14 | 0.173 |
IRF5 | 0.137 | 0.180 | |
COX2(PTGS2) | −0.044 | 0.627 | |
M2 Macrophage | CD163 | 0.16 | 0.117 |
VSIG4 | 0.097 | 0.345 | |
MS4A4A | 0.068 | 0.508 | |
Neutrophil | CD66b(CEACAM8) | −0.075 | 0.468 |
CD11b(ITGAM) | 0.26 | 0.010 | |
CCR7 | −0.084 | 0.412 | |
Natural killer cell | KIR2DL1 | 0.026 | 0.804 |
KIR2DL3 | 0.086 | 0.405 | |
KIR2DL4 | 0.125 | 0.224 | |
KIR3DL1 | 0.084 | 0.412 | |
KIR3DL2 | 0.112 | 0.276 | |
KIR3DL3 | 0.045 | 0.665 | |
Dendritic cell | HLA-DPB1 | 0.165 | 0.106 |
HLA-DQB1 | 0.124 | 0.226 | |
HLA-DRA | 0.284 | 0.005 | |
HLA-DPA1 | 0.25 | 0.013 | |
BDCA-1(CD1C) | −0.006 | 0.951 | |
BDCA-1(NRP1) | 0.007 | 0.947 | |
CD11c(ITGAX) | 0.046 | 0.654 | |
CD11b (ITGAM) | 0.26 | 0.010 | |
Th1 | IL12A | 0.095 | 0.357 |
IL1B | 0.472 | 0.000a | |
T-bet(TBX21) | 0.008 | 0.941 | |
STAT4 | −0.029 | 0.781 | |
STAT1 | 0.221 | 0.029 | |
IFN-gamma(IFNG) | 0.102 | 0.322 | |
TNF-alpha(TNF) | 0.175 | 0.087 | |
Th2 | GATA3 | 0.019 | 0.854 |
STAT6 | 0.136 | 0.185 | |
STAT5A | 0.083 | 0.419 | |
IL13 | 0.219 | 0.031 | |
Tfh | BCL6 | −0.237 | 0.020 |
IL21 | 0.029 | 0.775 | |
Th17 | STAT3 | 0.226 | 0.026 |
IL17A | 0.136 | 0.185 | |
Treg | FOXP3 | 0.064 | 0.536 |
CCR8 | 0.146 | 0.152 | |
STAT5B | −0.142 | 0.165 | |
TGFbeta(TGFB1) | −0.077 | 0.455 | |
CD25(IL2RA) | 0.163 | 0.112 | |
CD4 | 0.100 | 0.332 | |
Mast cells | TPSB2 | 0.407 | 0.000a |
TPSAB1 | 0.397 | 0.000a | |
CPA3 | 0.025 | 0.811 | |
MS4A2 | −0.077 | 0.452 | |
HDC | −0.113 | 0.272 |
Note: aP < 0.001.