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. 2021 Nov 1;12:782775. doi: 10.3389/fimmu.2021.782775

Figure 1.

Figure 1

Manufacturing procedures of CAR-T cells. T cells are firstly collected from the peripheral blood of the patients. The activated and amplified T cells are genetically engineered with CAR structure via retroviral, lentivirus or other vectors. CAR-T cells are then expanded ex vivo and a quality control procedure is applied. Finally, those modified T cells were infused back into the patients.