Skip to main content
. 2021 Nov 1;11:715677. doi: 10.3389/fonc.2021.715677

Table 9.

Correlation between miR-146a and miR-155 expression with the level of cytokines, Treg, and CD3+CTLA-4+ cells in patients based on genotypes.

Parameter Genotype N miR-146a Expression Genotype N miR-155 Expression
Pearson correlation(r) P value(2-tailed) Pearson correlation(r) P value(2-tailed)
IL-1β (pg/ml) GG 11 0.74 0.009 TT 19 0.58 0.009
GC 14 −0.30 0.29 AT 10 −0.25 0.48
CC 8 −0.08 0.84 AA 4 −0.22 0.77
IL-6 (pg/ml) GG 11 −0.34 0.30 TT 19 −0.21 0.38
GC 14 −0.27 0.35 AT 10 −0.25 0.48
CC 8 0.22 0.59 AA 4 −0.54 0.45
TNF-α (pg/ml) GG 11 −0.16 0.62 TT 19 −0.7 0.76
GC 14 −0.21 0.46 AT 10 * *
CC 8 −0.29 0.47 AA 4 −0.89 0.10
IFN-γ (pg/ml) GG 11 −0.17 0.60 TT 19 0.01 0.96
GC 14 −0.28 0.31 AT 10 −0.22 0.53
CC 8 −0.09 0.82 AA 4 0.68 0.31
IL-4 (pg/ml) GG 11 0.10 0.75 TT 19 * *
GC 14 * * AT 10 −0.07 0.83
CC 8 * * AA 4 * *
TGF-β (pg/ml) GG 11 −0.57 0.06 TT 19 0.15 0.52
GC 14 −0.26 0.35 AT 10 −0.16 0.64
CC 8 −0.21 0.60 AA 4 −0.31 0.68
Treg Cells (%) GG 5 −0.87 0.05 TT 6 0.56 0.24
GC 5 0.61 0.26 AT 6 0.21 0.68
CC 5 −0.02 0.96 AA 3 0.60 0.58
CD3+CTLA4+ Cells (%) GG 11 −0.05 0.86 TT 19 −0.15 0.53
GC 14 0.09 0.73 AT 10 0.75 0.01
CC 8 0.79 0.01 AA 4 −0.54 0.45

Data are analyzed using linear regression, and r values are from Pearson’s correlation coefficient test.

*Cannot be computed because at least one of the variables is constant.

The values in red font are significant.