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. 2021 Nov 1;9:720536. doi: 10.3389/fcell.2021.720536

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Copyright © 2021 Borges, Link, Engstler and Jones.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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General structures of free GPIs (GIPLs) and LPGs. The dashed lines indicate smaller GIPL species in Leishmania (McConville and Ferguson, 1993). M_X indicates the number of mannoses and iM the unusual α1-3 binding of these mannoses. The number of phosphosaccharide repeats (n) of Leishmania LPGs is stage and species specific (Forestier et al., 2014). (A) Trypanosoma cruzi Type-1 GIPL, (B) Leishmania Type-1 GIPLs, (C) Leishmania Type-2 GIPLs, (D) Leishmania hybrid GIPLs, and (E) Leishmania LPGs.