Table 1.
Intervention and comparators.
| Treatment | Indication | Regimen | Price |
|---|---|---|---|
| [177Lu]Lu-DOTA-TATE (Lutathera®) | GI-NETs and P-NETs | 4 administrations of 7.4 GBq (200 mCi), once every 8 weeks [28] | 29.6 GBq (800 mCi) = £71,500 |
| Standard of care (SoC) | GI-NETs and P-NETs | 60 mg Octreotide LAR (Sandostatin®), once every 28-day cycle | 30 mg vial = £998.41 |
| Everolimus (Afinitor®) | GI-NETs and P-NETs | 10 mg administered once daily, until progression [6] | 30-tab, 10 mg packs = £2673 |
| Sunitinib (Sutent®) | GI-NETs and P-NETs | 37.5 mg administered once daily, until progression [7] | 30-tab, 12.5 mg packs = £784.70 |
GI-NETs, neuroendocrine tumours located in the gastrointestinal tract; P-NETs, neuroendocrine tumours located in the pancreas.