TABLE 3.
Paired t-tests between patients and controls for T1 relaxation times measured in brain hemisphere contralateral or ipsilateral to the more affected body side as indicated.
Region of Interest | Ipsilateral |
Contralateral |
|||||||||
N 1 | Patient |
Control |
p | Patient |
Control |
p | |||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | ||||
Prefrontal Subcortical Area | 19 | 1, 026.79 | 191.32 | 849.45 | 159.89 | 0.0085* | 1, 059.11 | 184.49 | 869.33 | 123.54 | 0.0011** |
Subcortical Primary Motor Area | 20 | 995.67 | 129.37 | 938.36 | 71.28 | 0.078 | 993.04 | 97.61 | 936.28 | 128.63 | 0.0488* |
Supplementary Motor Area | 19 | 1, 187.13 | 235.93 | 1, 064.81 | 249.25 | 0.19 | 1, 232.19 | 196.85 | 1, 055.84 | 289.86 | 0.0097* |
Centrum Semiovale | 20 | 1, 126.00 | 120.97 | 995.42 | 90.25 | 0.0011** | 1, 118.82 | 119.01 | 996.74 | 120.52 | 0.0008** |
Splenium Corporis Callosi | 20 | 1, 420.66 | 123.40 | 1, 293.15 | 148.74 | 0.0052* | 1, 422.51 | 142.67 | 1, 279.92 | 153.91 | 0.0023** |
Nucleus Caudatus | 20 | 2, 002.53 | 183.38 | 1, 938.72 | 188.31 | 0.27 | 2, 111.10 | 169.36 | 1, 978.04 | 148.02 | 0.0177* |
Putamen | 20 | 1, 933.18 | 173.99 | 1, 795.14 | 139.92 | 0.0102* | 1, 974.17 | 164.92 | 1, 825.39 | 200.67 | 0.0203* |
Globus Pallidus | 20 | 1, 612.88 | 219.98 | 1, 548.07 | 174.52 | 0.33 | 1, 634.94 | 172.93 | 1, 563.41 | 211.27 | 0.24 |
Thalamus | 20 | 2, 443.62 | 331.26 | 2, 375.49 | 256.63 | 0.47 | 2, 384.40 | 307.89 | 2, 309.73 | 338.12 | 0.4 |
Mesencephalon | 19 | 1, 863.19 | 246.24 | 1, 772.37 | 162.36 | 0.17 | 1, 861.59 | 151.66 | 1, 747.23 | 180.17 | 0.0391* |
Upper Pons | 20 | 1, 863.93 | 186.70 | 1, 737.71 | 156.43 | 0.0172* | 1, 845.78 | 192.32 | 1, 839.76 | 181.69 | 0.9 |
Lower Pons | 20 | 1, 981.60 | 265.19 | 1, 876.63 | 191.22 | 0.16 | 1, 893.47 | 205.50 | 1, 843.12 | 235.43 | 0.4 |
Cerebellar White Matter | 20 | 1, 693.94 | 178.22 | 1, 606.62 | 182.62 | 0.15 | 1, 535.96 | 183.33 | 1, 572.04 | 194.26 | 0.49 |
Cerebellar Posterior Lobe | 20 | 1, 678.96 | 312.26 | 1, 669.21 | 186.02 | 0.9 | 1, 471.78 | 270.08 | 1, 473.91 | 262.18 | 0.98 |
1Number of patient-control pairs.
**Significant after correction for multiple comparisons by using false-discovery rate (FDR).
*p < 0.05 but not significant after FDR correction.