TABLE 4.

Paired t-tests between patients and controls for brain T2 relaxation times measured in brain hemisphere contralateral or ipsilateral to the more affected body side as indicated.

Region of Interest		Ipsilateral					Contralateral
	N 1	Patient		Control		p	Patient		Control		p
		Mean	SD	Mean	SD		Mean	SD	Mean	SD
Prefrontal Subcortical Area	14	137.32	16.57	146.20	18.29	0.22	132.25	22.50	142.55	16.30	0.14
Subcortical Primary Motor Area	19	123.38	9.54	119.49	13.80	0.35	116.70	12.68	121.50	10.83	0.27
Supplementary Motor Area	19	111.63	14.26	119.77	10.74	0.07	116.23	19.30	123.29	12.39	0.24
Centrum Semiovale	20	124.06	9.70	127.91	7.52	0.16	123.49	11.45	127.12	9.21	0.3
Splenium Corporis Callosi	19	124.53	17.13	107.49	9.99	0.0005**	118.14	25.42	107.41	9.92	0.09
Nucleus Caudatus	19	98.66	8.75	100.13	5.28	0.58	101.71	8.00	99.86	5.74	0.47
Putamen	20	91.29	7.07	87.50	5.90	0.07	89.39	6.39	88.41	5.89	0.58
Globus Pallidus	18	75.20	5.19	72.99	5.18	0.2	73.95	9.37	74.95	7.53	0.74
Thalamus	20	108.63	10.94	104.51	5.22	0.12	107.27	7.64	104.52	8.35	0.27
Mesencephalon	18	94.70	8.97	94.90	14.16	0.9	93.05	9.06	92.97	8.47	0.98
Upper Pons	20	129.84	13.85	115.53	7.97	0.0011**	132.30	20.47	114.64	8.17	0.0013**
Lower Pons	17	126.65	21.00	124.91	17.44	0.8	123.86	15.58	120.21	14.33	0.44
Cerebellar White Matter	20	142.69	16.88	132.07	6.62	0.0145*	140.88	18.43	133.61	9.58	0.12
Cerebellar Posterior Lobe	17	137.90	15.20	136.88	11.28	0.79	143.65	24.95	131.93	13.88	0.08

¹Number of patient-control pairs.

**Significant after correction for multiple comparisons by using false-discovery rate (FDR).

*p < 0.05 but not significant after FDR correction.