TABLE 5.
Paired t-tests between patients and controls for T2′ measured in brain hemisphere contralateral or ipsilateral to the more affected body side as indicated.
Region of Interest | Ipsilateral |
Contralateral |
|||||||||
N 1 | Patient |
Control |
p | Patient |
Control |
p | |||||
Mean | SD | Mean | SD | Mean | SD | Mean | SD | ||||
Prefrontal Subcortical Area | 5 | 81.16 | 17.06 | 83.45 | 12.09 | 0.85 | 84.05 | 12.91 | 83.60 | 12.66 | 0.94 |
Subcortical Primary Motor Area | 17 | 56.00 | 7.27 | 57.10 | 10.60 | 0.70 | 60.73 | 10.73 | 59.03 | 8.00 | 0.63 |
Supplementary Motor Area | 13 | 66.68 | 15.24 | 64.86 | 9.75 | 0.67 | 67.57 | 8.51 | 74.06 | 9.21 | 0.0214* |
Centrum Semiovale | 17 | 69.58 | 8.41 | 69.53 | 7.31 | 0.99 | 70.72 | 10.79 | 69.64 | 11.34 | 0.77 |
Splenium Corporis Callosi | 18 | 53.85 | 12.63 | 51.68 | 7.62 | 0.40 | 55.92 | 11.71 | 48.51 | 7.26 | 0.024* |
Nucleus Caudatus | 16 | 57.79 | 12.06 | 56.19 | 8.28 | 0.65 | 58.62 | 18.24 | 61.98 | 15.36 | 0.63 |
Putamen | 17 | 47.21 | 9.53 | 49.73 | 14.36 | 0.53 | 49.56 | 11.51 | 44.67 | 8.44 | 0.21 |
Globus Pallidus | 10 | 36.15 | 5.15 | 33.84 | 8.85 | 0.56 | 34.68 | 6.20 | 27.32 | 5.81 | 0.0054* |
Thalamus | 13 | 69.80 | 11.49 | 71.41 | 8.05 | 0.69 | 73.98 | 9.72 | 74.88 | 14.18 | 0.86 |
Mesencephalon | 5 | 30.22 | 7.01 | 28.39 | 10.06 | 0.80 | 28.59 | 8.10 | 37.24 | 8.20 | 0.035* |
Upper Pons | 11 | 24.96 | 9.64 | 25.80 | 8.68 | 0.84 | 26.11 | 9.70 | 30.57 | 10.63 | 0.40 |
Lower Pons | 17 | 41.54 | 18.20 | 38.66 | 12.11 | 0.53 | 38.47 | 13.63 | 37.89 | 11.75 | 0.89 |
Cerebellar White Matter | 15 | 46.88 | 18.83 | 41.98 | 12.24 | 0.44 | 46.66 | 16.29 | 40.63 | 9.61 | 0.17 |
Cerebellar Posterior Lobe | 15 | 41.26 | 12.45 | 37.85 | 21.22 | 0.61 | 44.40 | 13.48 | 40.45 | 15.92 | 0.41 |
1Number of patient-control pairs.
**Significant after correction for multiple comparisons by using false-discovery rate (FDR).
*p < 0.05 but not significant after FDR correction.