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. 2021 Nov 1;11:749905. doi: 10.3389/fcimb.2021.749905

Table 1.

Baseline characteristics and risk factors of pulmonary co-infection.

Fungal and bacterial co-infection Fungal infection Univariable OR a (95% CI b ) P value Multivariable OR (95% CI) P value
Age (years) 43.04 ± 18.2 40.77 ± 18.8 0.580
Sex
 Male 32 (66.7%) 40 (56.3%) 1.55
(0.72–3.32)
0.258
 Female 16 (33.3%) 31 (43.7%)
Immune function
 Normal 5 (10.4%) 18 (25.4%) 2.92
(1.00–8.51)
0.043 3.20
(1.07–9.62)
0.038
 Defective 43 (89.6%) 53 (74.6%)
Antibacterial treatment 31 (64.6%) 48 (67.6%) 0.874
(0.40–1.89)
0.732
CT image manifestation
(Cavity lesions)
13 (27%) 9 (12.7%) 2.56
(0.99–6.59)
0.047 2.81
(1.06–7.49)
0.039
Isolated viruses 10 (20.8%) 11 (15.5%) 0.453
Fungus species
Aspergillus 21 (43.8%) 26 (36.6%) 0.591 c
Pneumocystis 11 (22.9%) 19 (26.8%)
Rhizopus 9 (18.8%) 12 (16.9%)
Cryptococcus 3 (6.3%) 8 (11.3)
Lichtheimia 2 (4.2%) 3 (4.2%)
Penicillium 1 (2%) 2 (2.8%)
Mucor 1 (2%) 0 (0%)
Scedosporium 0 (0%) 1 (1.4%)
a

OR, odds ratio.

b

CI, confidence interval.

c

Calculated by t-test.