Table 2.

Plasma cytokine, chemokine, and growth factor levels in preterm and term infants*.

Pro-inflammatory cytokines	Preterm N = 25	Term N = 25	p
IL-1β	0.24 (0.17-0.35)	0.40 (0.22-0.84)	0.04
IL-2	0.45 (0.45-3.63)	0.45 (0.45-3.30)	0.83
IL-6	2.27 (1.59-3.07)	3.46 (2.12-10.60)	0.05
IL-12	13.89 (9.94021.42)	18.62 (11.11-25.34)	0.16
IL-15	24.97 (5.35-49.47)	4 (4-28.15)	0.02
IL-17A	7.82 (5.36-10.54)	13.98 (11.11-22.86)	<0.0001
IFN-γ	19.72 (15.94-26.17)	21.29 (15.69-28.75)	0.88
TNF-α	17.08 (12.32-22.58)	15.96 (11.32-22.38)	0.75
Anti-inflammatory cytokines
IL-1RA	175.10 (120.2-250.5)	167.50 (119.3-214.2)	0.72
IL-4	1.30 (1.05-1.69)	1.26 (1.04-1.57)	0.79
IL-5	1.25 (1.25-4.96)	1.25 (1.25-3.06)	0.30
IL-7	7.73 (4.04-9.72)	5.96 (4.73-9.42)	0.72
IL-9	8.26 (6.59-10.78)	8.60 (7.61-12.11)	0.27
IL-10	1.66 (1.03-3.10)	1.86 (0.95-2.57)	0.85
IL-13	0.85 (0.52-1.23)	0.97 (0.53-1.22)	0.92
Chemokines
IL-8	20.90 (11.61-41.05)	57.41 (34.68-214.4)	0.001
Eotaxin	2.69 (1.96-2.95)	3.51 (2.73-4.74)	0.001
MIP-1α	0.38 (0.17-0.90)	1.64 (0.84-3.69)	0.0003
MIP-1β	8.40 (4.63-11.89)	13.65 (10.00-26.64)	0.003
MCP-1	22.26 (15.93-28.71)	12.3 (10.37-19.20)	0.0002
RANTES	147.5 (124.1-186.7)	164.0 (144.3-208.0)	0.20
IP-10	72.25 (44.96-102.8)	73.96 (58.35-104.20)	0.37
Growth Factors
G-CSF	64.84 (38.88-73.96)	52.65 (35.84-71.64)	0.16
FGF Basic	23.03 (5.80-37.72)	32.65 (16.74-44.19)	0.12
PDGF	789 (596-1391)	1437 (1064-2202)	0.001
VEGF	226.4 (60.56-359.20)	233.6 (167.0-397.9)	0.41

*All data are presented as median (IQR).

Bold values represent significantly different cytokines, chemokines and growth factors.