Table 3.

PANSS total and subscale scores at baseline, week 4, week 8, and week 12 in the betahistine and placebo groups.

	Betahistine group	Placebo group	Time F (p-value)	Group F (p-value)	Group*Time F (p-value)
PANSS total score			7.51 (<0.01)	0.28 (0.60)	1.82 (0.16)
Baseline	74.77 ± 14.48	75.34 ± 13.56
Week 4	72.79 ± 13.17	75.27 ± 13.23
Week 8	72.84 ± 12.22	74.41 ± 13.51
Week 12	72.53 ± 11.96	73.82 ± 13.12
Positive subscale score			2.11 (0.11)	2.18 (0.14)	1.59 (0.20)
Baseline	16.98 ± 5.20	18.16 ± 5.06
Week 4	17.00 ± 4.79	18.89 ± 4.92
Week 8	16.98 ± 4.74	18.75 ± 5.07
Week 12	16.91 ± 4.84	18.20 ± 4.71
Negative subscale score			28.41 (<0.01)	0.22 (0.64)	1.60 (0.20)
Baseline	23.23 ± 8.08	23.30 ± 7.32
Week 4	21.93 ± 7.26	22.86 ± 6.75
Week 8	21.63 ± 6.83	22.52 ± 6.79
Week 12	20.63 ± 6.31	21.55 ± 6.69
General subscale score			5.45 (0.01)	0.30 (0.59)	0.85 (0.40)
Baseline	34.56 ± 7.07	33.89 ± 6.45
Week 4	33.86 ± 6.84	33.52 ± 6.59
Week 8	34.23 ± 6.19	33.14 ± 6.68
Week 12	35.00 ± 6.32	34.07 ± 6.40