Skip to main content
. 2021 Nov 1;11:778557. doi: 10.3389/fonc.2021.778557

Table 3.

Risk based chi-square test of clinical characteristics.

Covariates Risk Total High Low Chi P-value
Age ≤65 118 (43.87%) 62 (46.97%) 56 (40.88%) 0.7814 0.376698
Age >65 151 (56.13%) 70 (53.03%) 81 (59.12%)
Gender Female 103 (38.29%) 49 (37.12%) 54 (39.42%) 0.0685 0.793606
Gender Male 166 (61.71%) 83 (62.88%) 83 (60.58%)
Grade G1–2 98 (36.43%) 49 (37.12%) 49 (35.77%) 0.0108 0.917084
Grade G3 171 (63.57%) 83 (62.88%) 88 (64.23%)
Stage Stages I–II 124 (46.1%) 58 (43.94%) 66 (48.18%) 0.3299 0.565703
Stage Stages III–IV 145 (53.9%) 74 (56.06%) 71 (51.82%)
T T1–2 68 (25.28%) 31 (23.48%) 37 (27.01%) 0.2748 0.600126
T T3–4 201 (74.72%) 101 (76.52%) 100 (72.99%)
M M0 253 (94.05) 122 (92.42) 131 (95.62) 0.7228 0.395234
M M1 16 (5.95%) 10 (7.58%) 6 (4.38%)
N N0–1 153 (56.88) 75 (56.82%) 78 (56.93%) 0 1
N N2–3 116 (43.12) 57 (43.18%) 59 (43.07%)
FPI ≤0 108 (40.15) 73 (55.3%) 35 (25.55%) 23.5476 1.00E-06
FPI >0 161 (59.85) 59 (44.7%) 102 (74.45%)
TIDE <0 84 (31.23%) 32 (24.24%) 52 (37.96%) 5.266 0.021746
TIDE >0 185 (68.77%) 100 (75.76 85 (62.04%)
TMB High TMB 135 (50.19%) 51 (38.64%) 84 (61.31%) 12.937 0.000322
TMB Low TMB 134 (49.81%) 81 (61.36%) 53 (38.69%)
ESTIMATE score High 134 (49.81%) 75 (56.82%) 59 (43.07%) 4.5507 0.032905
ESTIMATE score Low 135 (50.19%) 57 (43.18%) 78 (56.93%)
Immune score High 134 (49.81%) 66 (50%) 68 (49.64%) 0 1
Immune score Low 135 (50.19%) 66 (50%) 69 (50.36%)

TMB, tumor mutation burden; FPI, ferroptosis potential index; TIDE, tumor immune dysfunction and exclusion.