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. 2021 Nov 1;15:716887. doi: 10.3389/fnins.2021.716887

TABLE 3.

Hierarchical linear regression analyses examining the association between autistic traits (SRS) and ADHD symptoms (C3) on pain interference (PII), depression (CES-DC), and HRQoL (PedsQL) (n = 146a), adjusted for gender, age, and pain intensity (LPQ).

Unstandardizedb Standardized coefficients Betab
Dependents Step Predictors R 2 R2 Change F Change (df) Sig. F Change B SE β t Sig.
PedsQL 1 Controls 0.085 0.085 6.32 (2,137) 0.002
Gender −6.058 3.049 −0.149 −1.99 0.049
Age −1.13 0.584 −0.144 −1.93 0.055
2 Pain 0.128 0.044 6.84 (1,136) 0.01
Pain intensity −0.278 0.103 −0.201 −2.71 0.008
3 ASD/ADHD 0.271 0.143 13.13 (2,134) 0.000
C3 −0.326 0.131 −0.227 −2.50 0.014
SRS −0.364 0.165 −0.205 −2.21 0.029
CES-DC 1 Controls 0.084 0.084 6.27 (2,137) 0.002
Gender 3.12 2.107 0.112 1.48 0.141
Age 0.943 0.404 0.176 2.34 0.021
2 Pain 0.102 0.018 2.75 (1,136) 0.099
Pain intensity 0.118 0.071 0.125 1.66 0.099
3 ASD/ADHD 0.254 0.152 13.61 (2,134) 0.000
C3 0.213 0.09 0.217 2.36 0.02
SRS 0.277 0.114 0.228 2.44 0.016
PII 1 Controls 0.08 0.08 5.92 (2,137) 0.003
Gender 2.426 1.63 0.113 1.49 0.139
Age 0.692 0.312 0.167 2.22 0.028
2 Pain 0.14 0.061 9.59 (1,136) 0.002
Pain intensity 0.174 0.055 0.238 3.16 0.002
3 ASD/ADHD 0.253 0.113 10.16 (2,134) 0.000
C3 0.142 0.07 0.186 2.02 0.045
SRS 0.187 0.088 0.199 2.12 0.036

aPain intensity, n = 140 measured with the Lübeck Pain Questionnaire (LPQ).

bResults are displayed from the final model.

C3, Conners 3; SRS, The Social Responsiveness Scale; PII, Pain Interference Index; CES-DC, Center for Epidemiological Studies – Depression Scale Children; PedsQL, Pediatric Quality of Life Inventory; Sig., significance.