TABLE 5.

Total, direct and indirect effects of autistic traits (SRS) and ADHD symptoms (C3) on depression (CES-DC), pain interference (PII), and HRQoL (PedsQL), using psychological inflexibility (PIPS) as mediator with adjustment for age, gender, and level of pain intensity (LPQ) (n = 146).

Mediator: PIPS						Indirect effecta
X	Y	a path coefficient	b path coefficient	Total effect (c)	Direct effect (c′)	Effect (SE)	CI (99%)
							LLCI	ULCI
C3	CES	0.342**	0.454**	0.340**	0.185**	0.155** (0.044)	0.052	0.282
	PII	0.342**	0.414**	0.227**	0.086	0.142** (0.036)	0.050	0.240
	PedsQL	0.342**	−0.722**	−0.494**	−0.247**	–0.247** (–0.069)	–0.439	–0.079
SRS	CES	0.556**	0.455**	0.432**	0.180*	0.253** (0.056)	0.114	0.409
	PII	0.556**	0.422**	0.290**	0.055	0.235** (0.048)	0.109	0.362
	PedsQL	0.556**	0.734**	−0.602**	–0.194	–0.408** (0.087)	–0.661	–0.184

Number of bootstrap resamples = 5000; Covariates in all analyses: age, gender, pain intensity; LLCI/ULCI, Lower/Upper Level Confidence Interval; C3, Conners 3; SRS, The Social Responsiveness Scale; PII, Pain Interference Index; CES-DC, Center for Epidemiological Studies – Depression Scale Children; PedsQL, Pediatric Quality of Life Inventory.

^aThe indirect effect is statistically significant when the confidence interval (LLCI – ULCI) does not include zero (99% equals p < 0.01 level significance). *p < 0.05 and **p < 0.01.