Table 7.
Association between ALB, ALT, AST, and total bilirubin with prognosis of cardiac surgery patients without liver disease.
| Outcome | OR | 95% CI | P-value | |
|---|---|---|---|---|
| Hospital mortality | ||||
| ALB | Model 1 | 0.48 | 0.33–0.70 | 0.000 |
| Model 2 | 0.43 | 0.29–0.62 | 0.000 | |
| ALT | Model 1 | 1.00 | 1.00–1.01 | 0.003 |
| Model 2 | 1.00 | 1.00–1.01 | 0.004 | |
| AST | Model 1 | 1.00 | 1.00–1.01 | 0.002 |
| Model 2 | 1.00 | 1.00–1.01 | 0.005 | |
| Total bilirubin | Model 1 | 1.33 | 1.07–1.65 | 0.010 |
| Model 2 | 1.45 | 1.19–1.78 | 0.000 | |
| 90-day mortality | ||||
| ALB | Model 1 | 0.46 | 0.35–0.61 | 0.000 |
| Model 2 | 0.42 | 0.31–0.55 | 0.000 | |
| ALT | Model 1 | 1.00 | 1.00–1.01 | 0.015 |
| Model 2 | 1.00 | 1.00–1.01 | 0.008 | |
| AST | Model 1 | 1.00 | 1.00–1.01 | 0.007 |
| Model 2 | 1.00 | 1.00–1.01 | 0.008 | |
| Total bilirubin | Model 1 | 1.29 | 1.07–1.54 | 0.006 |
| Model 2 | 1.40 | 1.18–1.65 | 0.000 | |
| 4-year mortality | ||||
| ALB | Model 1 | 0.47 | 0.37–0.58 | 0.000 |
| Model 2 | 0.48 | 0.38–0.59 | 0.000 | |
| ALT | Model 1 | 1.00 | 0.99–1.19 | 0.793 |
| Model 2 | 1.00 | 0.99–1.00 | 0.647 | |
| AST | Model 1 | 1.00 | 0.99–1.00 | 0.286 |
| Model 2 | 1.00 | 0.99–1.00 | 0.304 | |
| Total bilirubin | Model 1 | 1.37 | 1.15–1.64 | 0.001 |
| Model 2 | 1.48 | 1.23–1.77 | 0.000 | |
Model 1 was adjusted for SOFA score, creatinine, SpO2, hypertension, congestive heart failure, and chronic pulmonary.
Model 2 was adjusted for height, SBP, and SAPS II score.
For 4-year mortality, only patients in the CareVue system who were followed for at least 4-year were analyzed.