Table 5.
List of targets with reference ligands for in-silico study.
| Target Protein & PDB ID | Protein Function | Organism | Resolution | Reference Ligand |
|---|---|---|---|---|
| Alpha-Glucosidase, 2QMJ | Catalyze the final glucose releasing step in starch digestion | Homo Sapiens | 1.90 Å | Acarbose |
| Alpha-Amylase, 1B2Y | Catalyzes the hydrolyses of Polysaccharides | Homo Sapiens | 3.20 Å | Acarbose |
| Xanthine Oxidase, 3NVY | Generate reactive oxygen species | Bos Taurus | 2.00 Å | Quercetin |
| Cyclooxygenase 1, 1EQG | Produce prostaglandins | Homo Sapiens | 2.61 Å | Ibuprofen |
| Thrombin Enzyme, 2A2X | Catalyze blood coagulation cascade | Homo Sapiens | 2.44 Å | NA9 |
| Angiotensin Receptor, 4ZUD | Involved in controlling blood pressure | Homo Sapiens | 2.80 Å | Olmesartan |