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. 2021 Nov 1;9:673993. doi: 10.3389/fcell.2021.673993

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Copyright © 2021 Wang, Zhou, Chen, Luo, Guo, Wang, Yang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification and characterization of OMVs from H. pylori. (A) Electron micrographs of OMVs from H. pylori. Isolated OMVs from H. pylori were fixed with negative staining with Na-phosphotungstate, and observed by transmission electron microscope. (B) CagA expression in H. pylori-derived OMVs (CagA⁺: OMVs from CagA-positive H. pylori; CagA^–: OMVs from CagA-negative H. pylori). (C) LPS levels in H. pylori-derived OMVs and vehicle were determined by ELISA (n = 5, ^#P < 0.01 vs. control).