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. 2021 Nov 15;25:391. doi: 10.1186/s13054-021-03802-3

Fig. 2.

Fig. 2

Natural log transformation of odd ratios summarizing variables significantly associated with extubation outcome. A Overall analysis; B Sensitivity analysis focusing on studies defining extubation failure as death or reintubation, whatever the delay; C Sensitivity analysis focusing on studies defining extubation failure at 48 h. Natural log transformation of odd ratios (lnOR) were derived from crude OR (for binary variables) and from standardized mean differences (for continuous variables) to summarize the effect of 26 variables significantly associated with extubation outcome, involving three main functions [respiratory (blue bars), circulatory (red bars), neurological (orange bars) and scores/physiological data (grey bars)]. COPD: chronic obstructive pulmonary disease; BMI: body mass index; GCS: Glasgow coma scale; NIF: negative inspiratory force; SAPSII: simplified acute physiology score; RSBI: rapid shallow breathing index; SBT: spontaneous breathing trial; MEP: maximal expiratory pressure; MV: mechanical ventilation