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. 2021 Nov 15;25:391. doi: 10.1186/s13054-021-03802-3

Table 1.

Type of spontaneous breathing trial and definition of extubation failure

Variable Number of studies (%)
Spontaneous breathing trial
T piece 15 (22.4%)
Low pressure support with zero-end expiratory pressure 6 (9.0%)
Continuous positive airway pressure 3 (4.5%)
Other 33 (49.3%)
Not available 10 (14.8%)
Duration of SBT
30 min 12 (17.9%)
60 min 8 (11.9%)
120 min 13 (19.4%)
Variable* 21 (31.3%)
Not available 12 (17.9%)
Definition of SBT failure
Respiratory rate 43 (64.2%)
Increased breathing work or distress signs 31 (46.9%)
Arterial oxygen saturation 39 (58.2%)
PaO2 8 (11.9%)
PaCO2 10 (14.9%)
Tidal volume or minute ventilation or RSBI 11 (16.4%)
Heart rate 36 (53.7%)
Arterial pressure or introduction of vasopressive drug 36 (53.7%)
Neurological criteria 38 (56.7%)
Not available 20 (29.9%)
Definition of extubation failure
Death or reintubation
 Within 24 h 4 (6.0%)
 Within 48 h 30 (44.8%)
 Within 72 h 14 (20.9%)
 Within 7 days 5 (7.5%)
 At any time until discharge or death 4 (6.0%)
Reintubation or curative non-invasive mechanical ventilation 10 (14.9%)

SBT spontaneous breathing trial, PaO2 partial pressure of oxygen, PaCO2 partial pressure of carbon dioxide, RSBI Rapid Shallow Breathing Index, * from 30 min to 12 h