Table 1 (abstract P033) Results of correlation between BIA estimated fluid volumes and the volume of distribution of several antibiotics (separate and all antibiotics pooled)
Antibiotic | TBW (L) | ECW (L) | ICW (L) | ECW (%) |
---|---|---|---|---|
Amoxicillin/clavulanic acid (n = 10) |
45.85 ± 11.02; r = 0.90* [0.66;1.00] |
22.84 ± 6.31; r = 0.78* [-0.003;1.00] |
23.01 ± 5.31; r = 0.88* [0.55;1.00] |
49.55 ± 4.07; r = -0.042 [-0.80;0.81] |
Meropenem (n = 21) |
44.05 ± 9.78; r = 0.47* [0.03;0.76] |
22.49 ± 6.35; r = 0.43* [0.03;0.71] |
21.56 ± 3.65; r = 0.50* [0.21;0.71] |
50.43 ± 3.47; r = 0.25 [-0.21;0.59] |
Piperacillin/tazobactam (n = 16) |
39.90 ± 8.78; r = 0.34 [-0.22;0.73] |
19.33 ± 4.56; r = 0.51* [0.13;0.76] |
20.56 ± 4.48; r = 0.16 [-0.4;0.62] |
48.31 ± 2.66; r = 0.57* [0.04;0.86] |
Vancomycin (n = 21) |
40.87 ± 11.89; r = 0.28 [-0.22;0.70] |
20.06 ± 6.45; r = 0.20 [-0.30;0.61] |
20.81 ± 5.78; r = 0.29 [-0.20;0.67] |
48.90 ± 3.46; r = -0.21 [-0.66;0.28] |
Total – all antibiotics pooled (n = 68) |
42.36 ± 10.45; r = 0.33* [0.10;0.55] |
21.05 ± 6.05; r = 0.32* [0.09;0.53] |
21.31 ± 4.78; r = 0.33* [0.10;0.52] |
49.33 ± 3.42; r = 0.12 [-0.16;0.39] |
Values are represented as mean ± SD. ECW = extracellular water; ICW = intracellular water; r = correlation coefficient [95% confidence interval]; TBW = total body water. * p < 0.05