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. 2021 Nov 15;25(Suppl 1):383. doi: 10.1186/s13054-021-03769-1

Table 1 (abstract P033) Results of correlation between BIA estimated fluid volumes and the volume of distribution of several antibiotics (separate and all antibiotics pooled)

Antibiotic TBW (L) ECW (L) ICW (L) ECW (%)
Amoxicillin/clavulanic acid (n = 10)

45.85 ± 11.02;

r = 0.90* [0.66;1.00]

22.84 ± 6.31;

r = 0.78* [-0.003;1.00]

23.01 ± 5.31;

r = 0.88* [0.55;1.00]

49.55 ± 4.07;

r = -0.042 [-0.80;0.81]

Meropenem (n = 21)

44.05 ± 9.78;

r = 0.47* [0.03;0.76]

22.49 ± 6.35;

r = 0.43* [0.03;0.71]

21.56 ± 3.65;

r = 0.50* [0.21;0.71]

50.43 ± 3.47;

r = 0.25 [-0.21;0.59]

Piperacillin/tazobactam (n = 16)

39.90 ± 8.78;

r = 0.34 [-0.22;0.73]

19.33 ± 4.56;

r = 0.51* [0.13;0.76]

20.56 ± 4.48;

r = 0.16 [-0.4;0.62]

48.31 ± 2.66;

r = 0.57* [0.04;0.86]

Vancomycin (n = 21)

40.87 ± 11.89;

r = 0.28 [-0.22;0.70]

20.06 ± 6.45;

r = 0.20 [-0.30;0.61]

20.81 ± 5.78;

r = 0.29 [-0.20;0.67]

48.90 ± 3.46;

r = -0.21 [-0.66;0.28]

Total – all antibiotics pooled (n = 68)

42.36 ± 10.45;

r = 0.33* [0.10;0.55]

21.05 ± 6.05;

r = 0.32* [0.09;0.53]

21.31 ± 4.78;

r = 0.33* [0.10;0.52]

49.33 ± 3.42;

r = 0.12 [-0.16;0.39]

Values are represented as mean ± SD. ECW = extracellular water; ICW = intracellular water; r = correlation coefficient [95% confidence interval]; TBW = total body water. * p < 0.05