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. 2021 Nov 15;2021(11):CD004293. doi: 10.1002/14651858.CD004293.pub4

Comparison 23. Mizoribine ± steroids versus placebo/no treatment/corticosteroids.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
23.1 Complete or partial remission 2   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
23.1.1 Complete or partial remission at final follow‐up 2 114 Risk Ratio (M‐H, Random, 95% CI) 2.24 [1.14, 4.38]
23.1.2 Complete or partial remission at final follow‐up (≥ 2 years) 1 25 Risk Ratio (M‐H, Random, 95% CI) 4.71 [0.66, 33.61]
23.2 Complete remission 3   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
23.2.1 Complete remission at final follow‐up 3 150 Risk Ratio (M‐H, Random, 95% CI) 1.63 [0.69, 3.84]
23.2.2 Complete remission at final follow‐up (> 2 years) 1 25 Risk Ratio (M‐H, Random, 95% CI) 5.60 [0.32, 98.21]
23.3 Partial remission 2   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
23.3.1 Partial remission at final follow‐up 2 114 Risk Ratio (M‐H, Random, 95% CI) 1.89 [0.90, 3.97]
23.3.2 Partial remission at final follow‐up (≥ 2 years) 1 25 Risk Ratio (M‐H, Random, 95% CI) 2.36 [0.28, 19.66]
23.4 Temporary or permanent discontinuation/hospitalisation due to adverse events 1 89 Risk Ratio (M‐H, Random, 95% CI) 4.29 [0.21, 86.80]