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. 2021 Nov 15;2021(11):CD004293. doi: 10.1002/14651858.CD004293.pub4

ChiCTR‐INR‐17011400.

Study name The effect of the treatment of idiopathic membranous nephropathy was observed in the treatment of idiopathic membranous nephropathy, and the effect of the treatment on Th17 / Treg
Methods
  • Study design; parallel, open‐label RCT

  • Study duration: from May 2017

  • Duration of follow‐up: not reported

Participants
  • Setting: single centre

  • Country: China

  • Number: group 1 (40); group 2 (40)

  • Sex (M/F): both

  • Inclusion criteria: 18 to 70 years; 24‐hour urine protein is ≥ 3.5 g; SCr < 442 µmol/L; renal biopsy pathology of Sanjia hospital proved to be membranous nephropathy; a combination of the hormone combined immunosuppressant therapy for 3 months was invalid

  • Exclusion criteria: secondary membranous nephropathy; acute and chronic infectious diseases; malignant tumour; severe diabetes, hypertension, and liver dysfunction; pregnancy; mental illness

Interventions Group 1
  • Glucocorticoid + tacmox + Chinese medicine


Group 2
  • Glucocorticoid + tacosa treatment

Outcomes
  • 24 hours of urine protein quantification

Starting date
  • Registration site date last refreshed 14 May 2017

Contact information
  • liuyongzhidaifu@163.com

Notes
  • Not yet recruiting