Table 3.
Birth year (Infancy WFS) |
Difference in β (year 2008–2009) | P-Value for difference∗∗ | ||||
---|---|---|---|---|---|---|
2008 (High WFS) |
2009 (Low WFS) |
|||||
β (95% CI) | P-value∗ | β (95% CI) | P-value∗ | |||
Lung Function | ||||||
Inspiratory Capacity (mL/kg) | -4.01 (-8.46, 0.43) | 0.07 | 0.61 (-7.54, 8.76) | 0.88 | -4.62 | 0.30 |
Vital Capacity (mL/kg) | 4.97 (-3.03, 13.0) | 0.21 | -2.32 (-10.8, 6.15) | 0.57 | 7.29 | 0.20 |
Expiratory Reserve Volume (mL/kg) | 8.98 (2.84, 15.1) | 0.006 | -2.93 (-11.0, 5.18) | 0.46 | 11.91 | 0.018 |
Functional Residual Capacity (mL/kg) | 7.74 (2.19, 13.3) | 0.009 | -5.17 (-16.8, 6.51) | 0.37 | 12.91 | 0.039 |
Residual Volume (mL/kg) | 0.54 (-5.22, 6.30) | 0.85 | -1.78 (-13.1, 9.50) | 0.75 | 2.31 | 0.70 |
Total Lung Capacity (mL/kg) | 5.51 (-2.75, 13.8) | 0.18 | -4.1 (-19.4, 11.2) | 0.58 | 9.61 | 0.25 |
Tissue Compliance (/kg) | 2.1 × 10−4 (-1.9 × 10−4, 6.0 × 10−4) | 0.28 | -3.0 × 10−4 (-6.5 × 10−4, 4.3 × 10−5) | 0.08 | 5.1 × 10−4 | 0.051 |
Cytokine Response | ||||||
IL8 Secretion Level (pg/mL) | -375.4 (-2123.8, 1372.9) | 0.66 | 293.4 (-2011.7, 2598.5) | 0.79 | -668.8 | 0.63 |
IL6 Secretion Level (pg/mL) | 6.07 (-82.6, 94.8) | 0.89 | 2.28 (-79.3, 83.9) | 0.95 | 3.79 | 0.95 |
SE: standard error; 95% CI: 95% confidence interval.∗ rank: ranges from 0 (lowest) to 1 (highest rank). ∗∗ difference between coefficients, calculated by SAS proc glm procedure.
Bolded values were intended to highlight statistical significance.