Figure 3. Depletion of KCs is not sufficient to enhance early CHIKV dissemination.

1. WT or Clec4F‐DTR⁺ C57BL/6 mice were treated i.v. with DT prior to s.c. inoculation in the left‐rear footpad with 10³ PFU of CHIKV. Infectious virus was quantified at 24 hpi by FFA. Mean ± SEM. Data are pooled from two experiments, n = 8. Mann–Whitney test; P > 0.05.
2. WT C57BL/6 mice were treated i.v. with PLL or CLL 42 h prior to s.c. inoculation in the left‐rear footpad with 10³ PFU of CHIKV. Infectious virus at 24 hpi was quantified by FFA. Mean ± SD. Data are pooled from two experiments, n = 8. Mann–Whitney test; ***P < 0.001.