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. Author manuscript; available in PMC: 2021 Nov 15.
Published in final edited form as: Dev Dyn. 2019 Oct 24;249(3):281–297. doi: 10.1002/dvdy.118

Figure 2. Gene expression is segregated into 5 compartments across the radial axis on E13.5.

Figure 2.

(A) Gene expression pattern of Wnt4 and Gsc on the nonsensory roof of the duct. (B) Gene expression pattern of Bmp4 and Isl1 on the floor of the duct. (C) Overlay of images in A and B reveals that 5 compartments are already established on E13.5 to give rise to the future Reissner’s membrane (RM), the future stria vascularis (SV), the outer sulcus (OS), the sensory domain (S) and the inner sulcus (IS). Dual chromogenic in situ hybridizations were carried out using RNAScope®.