Table 10. In Vitro Metabolic Stability Across Species for Compound 23.
| species | mouse | rat | dog | human |
|---|---|---|---|---|
| microsome Clint (μL/min/mg protein) | <11.9 | <11.9 | 5.8 | <11.9 |
| hepatocyte Clint (μL/min/million cells) | n.d. | 0.7 | 2.4 | 0.5 |
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