Figure 2.

Mono-sodium urate–induced mechanical withdrawal threshold decreased and edema of left ankle in chickens of gouty arthritis. (a) 1 h after MSU injection, the left ankle of the chicken mechanical withdrawal threshold decreased. (b–d) After MSU injection, the stiffness score and circumference of the left ankle in chickens suffering gouty arthritis showed significant differences compared with the saline group. In the schematic diagram of ankle swelling (c) of the same scale (red area), after injection of MSU, the black arrow indicates that there is no edema, and the blue arrow indicates that there is edema. *p < 0.05, **p < 0.01, MSU (n = 8) vs. saline (n = 8).