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. 2021 Nov 11;17:17448069211047863. doi: 10.1177/17448069211047863

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — The effect of NB001 on spontaneous pain behaviors in chickens of gouty arthritis. (a) The schematic figures of administration route and time-line for peroral administration of NB001 or saline into chickens of gouty arthritis. (b) NB001 didn’t affect the number of spontaneous pain behavior on chickens with gouty arthritis. (c, d) NB001 decreased the total time in 5 min and the average time of each flinching and sitting in chickens with gouty arthritis. (e) NB001 significantly improved the limping behavior of chickens suffering gouty arthritis. *p < 0.05, **p < 0.01, MSU + saline (n = 8) vs. MSU + NB001 (n = 8).