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. 2021 Nov 2;12(11):1759–1765. doi: 10.1021/acsmedchemlett.1c00374

Table 2. Broad-Spectrum Anti-influenza Activity of Compounds 12c, 12e, 13c, and 13d.

    A/Hong Kong/4801/2014 (H3N2)
B/Sichuan/531/2018 (Victoria)
compound CC50 (μM) IC50 (μM) SI IC50 (μM) SI
12c >100 1.71 ± 0.44 >58.48 37.63 ± 2.03 >2.66
12e >100 1.20 ± 0.27 >83.33 >100
13c >100 2.67 ± 0.26 >37.45 28.35 ± 1.61 >3.53
13d >100 4.58 ± 0.13 >21.83 1.87 ± 0.23 >53.48
OSV-p >100 >100 >100