Skip to main content
. 2021 Oct 21;12(11):1694–1702. doi: 10.1021/acsmedchemlett.1c00304

Figure 13.

Figure 13

(A) (i) Binding pose of compound 20d (brown) in the active site of the VEGFR2 kinase receptor with important residues highlighted with gray sticks. (ii) Lig plot of compound 20d. (B) (i) Binding pose of compound 20a (brown) in the active site of the VEGFR2 kinase receptor with important residues highlighted with gray sticks. (ii) Lig plot of compound 20d. (C) (i) Binding pose of standard ligand (Sunitinib) (brown) shown in the active site of the VEGFR2 kinase receptor with important residues highlighted with gray sticks. (D) (i) Binding pose of standard Capsaicin (brown) with important residues enlightened with gray sticks. (ii) Lig plot of compound capsaicin. (E) Superimposition of the docking pose of 20a (green) with standard sunitinib (orange) and standard capsaicin (yellow) in the active site of the VEGFR2 kinase receptor.