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. 2021 Oct 21;12(11):1694–1702. doi: 10.1021/acsmedchemlett.1c00304

Table 4. IC50 Profile for Compounds 20a, 20d, and 22a, with Capsaicin and Doxorubicin.

  IC50
Tested compound HCT-116 NCI-H460 SKOV3
20a 8.55 (μM) 5.41 (μM) 6.4 (μM)
20d 10.50 (μM) 14.42 (μM) 12.51 (μM)
22a 13.4 (μM) 9.89 (μM) 31.4 (μM)
Capsaicin 40.16 (μM) 30.66 (μM) 22.03 (μM)
Doxorubicin 57.77 (nM) 4.29 (nM) 25.83 (nM)