Figure 4.
Cellular viability of the (a) murine melanoma cell line (B16F10), (b) human melanoma cell line (A375), and (c) human epidermal keratinocyte cell line (HaCaT) in the presence of two hybrid compounds, 13b and 13f, with potential antiproliferative properties. TMZ was used as a positive control. The compounds were incubated for 48 h, and the cell viability was determined by the MTS assay. The cell concentration was 1.5 × 103 cells/mL. The tested concentrations of all compounds were 20, 40, and 80 μM.