Table 2. PI3K Isoform Ki and PIM Isoform IC50 Dataa.
| Nr | PI3Kα | PI3Kβ | PI3Kδ | PI3Kγ | PIM-1 | PIM-2 | PIM-3 |
|---|---|---|---|---|---|---|---|
| 28 | 0.25 | 0.37 | 0.08 | 0.44 | 18.2 | 13.3 | 4.39 |
| 31 | 0.27 | 0.31 | 0.13 | 0.17 | 22.8 | 8.04 | 5.75 |
The values are the average of two independent experiments in nM. Ki for PI3K isoforms was determined with a HTRF technology assay. IC50 for PIM-1 was determined via ADP Hunter Plus assay.