Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 11;20:15330338211049903. doi: 10.1177/15330338211049903

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 4. — Differential characteristics of the lipid profile panel, composed of five lipids, were used for distinguishing SqCC tumor tissues from ANIT. (A) Area under the curve values obtained from univariate ROC analysis of the five lipids. PC(44:4), AUC = 0.893 (95% CI: 0.811-0.955); DAG(36:5), AUC = 0.858 (95% CI: 0.765-0.929); SM(d18:1/20:0), AUC = 0.858 (95% CI: 0.770-0.939); PI(46:7), AUC = 0.882 (95% CI: 0.798-0.949); Hexer-AP(t8:0/29:1 + O), AUC = 0.875 (95% CI: 0.797-0.943). (B) ROC curve with 10-fold cross-validation, illustrating the classification performance of the lipid profile panel for distinguishing between SqCC tumor tissues and ANIT. AUC: 0.913, 95% CI: 0.841-0.985, sensitivity: 0.875, and specificity: 0.925.

Abbreviations: SqCC, squamous cell carcinoma; ANIT, adjacent noninvolved tissues; ROC, receiver operating characteristic curve; AUC, area under the curve; CI, confidence interval; PC, phosphatidylcholine; DAG, diacylglycerol; SM, sphingomyelin; PI, phosphatidylinositol.