Fig. 4.

a Thermal withdrawal latencies of CFA-injected male mice treated with camphene (3.0 μg/i.t.), alpha-bisabolol (1.0 μg/i.t.) or control vehicle (10 ul/i.t). The dashed line and hashtag indicate the range of data points where PBS treated animals differed from the CFA treated group (## P < 0.01). b, c Data for thermal hyperalgesia of Cav3.2 null and WT mice when measured 45 min after treatment with b camphene (3.0 μg/i.t.) or c alpha-bisabolol (1.0 μg/i.t.). Each circle represents the mean ± S.E.M. (n = 4–9) and data are representative of 2 independent sets of experiments. Statistical analyses were performed by two-way, or three-way ANOVA followed by Tukey's test (*P < 0.05, **P < 0.01 relative to vehicle)