Table 5.
Clinical features and interventions associated with in-hospital mortality in CrKP sepsis with univariable and multivariable analysis.
| Variables | Univariable |
Multivariable fully adjusted model |
||
|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | |
| Age | 0.99 (0.96, 1.02) | 0.376 | NA | |
| Male | 0.34 (0.11, 1.07) | 0.064 | NA | |
| Comorbidities | 0.66 (0.21, 2.03) | 0.468 | 0.97 (0.27, 3.43) | 0.957 |
| Lymphocyte | 0.57 (0.28, 1.17) | 0.127 | 0.43 (0.19,0.96) | 0.040 |
| SOFA score | 1.81 (1.34, 2.44) | <0.001 | 1.15 (1.00, 1.33) | 0.053 |
| APACHE II score | 1.32 (1.14, 1.52) | <0.001 | 1.30 (1.13, 1.50) | <0.001 |
| PCT | 1.06 (0.97, 1.15) | 0.192 | 1.05 (0.97, 1.14) | 0.225 |
| Platelets | 0.99 (0.99, 1.00) | 0.026 | 0.99 (0.99, 1.00) | 0.046 |
| Total bilirubin | 1.03 (0.99, 1.06) | 0.150 | 1.02 (0.99, 1.06) | 0.156 |
| Creatinine | 1.00 (1.00, 1.01) | 0.107 | 1.00 (1.00, 1.01) | 0.072 |
| Lact | 2.65 (1.47, 4.78) | 0.001 | 2.75 (1.47, 5.12) | 0.002 |
| PCO2 | 0.95 (0.90, 1.01) | 0.120 | 0.96 (0.90, 1.02) | 0.176 |
| APTT | 1.16 (0.96, 1.40) | 0.129 | 1.13 (1.04, 1.23) | 0.005 |
| Comorbidities | NA | 0.97 (0.27, 3.43) | 0.957 | |
| Corticosteroid therapy | NA | 0.08 (0.02, 0.41) | 0.002 | |
| CRRT | NA | 3.71 (1.20, 11.43) | 0.022 | |
| Invasive ventilation | NA | 1.41 (0.49, 4.06) | 0.524 | |
SOFA: sequential organ failure assessment; APACHE II: acute physiology and chronic health evaluation II.
PCT: procalcitonin; Lact: lactic acid; APTT: activated partial thromboplastin time; CRRT: continuous renal replacement therapy; NA: not application, CrKP: carbapenem-resistant klebsiella pneumonia.