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BHD reduces renal fibrotic and inflammatory factors in STZ-induced diabetic mice. A Western blot and quantitative analysis. BHD reduced the expression of fibronectin (FN), collagen I (Col I), interleukin-1β (IL-1β) and TNF-α compared to that in DM. DM, diabetes mellitus. Irbesartan (IRB) was taken as a positive control. Data represent the means ± SEM for groups of six animals. *P < 0.05, **P < 0.01, ***P < 0.001 versus normal mice. #P < 0.05, ##P < 0.01, ###P < 0.001 versus DM mice
