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BHD reduces renal fibronectin and IL-1β in STZ-induced diabetic mice. A Immunohistochemistry of the fibronectin (FN) and B interleukin-1β (IL-1β). DM, diabetes mellitus. Irbesartan (IRB) was taken as a positive control. Data represent the means ± SEM for groups of six animals. Scale bar: 50 µm. *P < 0.05, **P < 0.01, ***P < 0.001 versus normal mice. #P < 0.05, ##P < 0.01, ###P < 0.001 versus DM mice
