Table 2.
Proportion of PACT Patients Performing at or Below the Mild/Moderate and Severe Ranges of Impairment Across Cognitive Tests by ICU Status
| Domain | Overall (N = 82), % impaired∗ |
Non-ICU (N = 34), % Impaired |
Post-ICU (N = 48), % Impaired |
|||
|---|---|---|---|---|---|---|
| Mild/Moderate | Severe | Mild/Moderate | Severe | Mild/Moderate | Severe | |
| RAVLT acquisition | 26.8 | 14.6 | 14.7 | 8.8 | 35.4 | 18.8 |
| RAVLT delayed recall | 26.8 | 14.6 | 14.7 | 8.8 | 35.4 | 18.8 |
| Oral Trail Making Test Part A | 35.4 | 25.6 | 32.4 | 20.6 | 37.5 | 29.2 |
| Oral Trail Making Test Part B | 15.9† | 13.4† | 11.8§ | 8.8§ | 18.8‖ | 16.7‖ |
| Number span forward | 1.2 | 1.2 | 0 | 0 | 2.1 | 2.1 |
| Number span backward | 13.4 | 4.9 | 8.8 | 2.9 | 16.7 | 6.3 |
| Letter-cued verbal fluency | 25.6‡ | 8.5‡ | 11.8§ | 2.9§ | 35.4 | 12.5 |
| Category-cued verbal fluency | 31.7‡ | 9.8‡ | 26.5§ | 5.9§ | 35.4 | 12.5 |
| Cognitive composite score | 13.4 | 1.2 | 5.9 | 2.9 | 18.8 | 0 |
Abbreviations: ICU = intensive care unit; PACT = Post-Acute COVID-19 Team; RAVLT = Rey Auditory Verbal Learning Test.
Mild/moderate and severe cognitive impairment were defined as performances ≥1.5 and ≥2 standard deviations below published age-adjusted normative means. Hence, 7% of normative control group participants would be expected to produce a score in the mild/moderate range of impairment on any single cognitive test, and 2% would be expected to produce a score in the severe range of impairment on any single cognitive test.
n = 77.
n = 81.
n = 33.
n = 44.